Ladybug (Brad Pitt) is an unlucky assassin determined to do his job peacefully after one too many gigs gone off the rails. Fate, however, may have other plans, as Ladybug's latest mission puts him on a collision course with lethal adversaries from around the globe-all with connected, yet conflicting, objectives-on the world's fastest train. The end of the line is just the beginning in this non-stop thrill-ride through modern-day Japan.